CXCR3/CXCL10 interactions in the development of hypersensitivity pneumonitis
Background Hypersensitivity pneumonitis (HP) is an interstitial lung disease caused by
repeated inhalations of finely dispersed organic particles or low molecular weight chemicals.
The disease is characterized by an alveolitis sustained by CD8 (+) cytotoxic T lymphocytes,
granuloma formation, and, whenever antigenic exposition continues, fibrosis. Although it is
known that T-cell migration into the lungs is crucial in HP reaction, mechanisms implicated in
this process remain undefined. Methods Using flow cytometry, immunohistochemistry …
repeated inhalations of finely dispersed organic particles or low molecular weight chemicals.
The disease is characterized by an alveolitis sustained by CD8 (+) cytotoxic T lymphocytes,
granuloma formation, and, whenever antigenic exposition continues, fibrosis. Although it is
known that T-cell migration into the lungs is crucial in HP reaction, mechanisms implicated in
this process remain undefined. Methods Using flow cytometry, immunohistochemistry …
[引用][C] CXCR3/CXCL10 interactions in the development of hypersensitivity pneumonitis
CXCR3/CXCL10 interactions in the development of hypersensitivity pneumonitis … CXCR3/CXCL10
interactions in the development of hypersensitivity pneumonitis …
interactions in the development of hypersensitivity pneumonitis …
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